Fasting Page #3

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or you need to have protein before bedtime

to build muscle mass.

- So on the flight back to the west coast,

I read it again for 4 hours.

It was on that flight that

I said, I gotta try this.

- So the simple experiment

that we did was we took

exactly identical set of mice --

- One group was eating ad libitum.

So they got to eat their

food throughout the day

whenever they wanted to eat it and there,

both these groups are

on a super size me diet,

like that guy from that movie.

- I started with a high fat

diet because there are 11,000

research papers published so

far where animals or humans

are given this fatty

food and this fatty food

causes different diseases

starting from diabetes, obesity,

liver damage, cancer, and IBD,

inflammatory bowel disease,

et cetera.

- The lean mouse, without a doubt,

became obese, gained weight.

The lean mouse that was on

the time restricted regime

actually stayed lean and that's really

what caught my attention.

- So even though they eat

the same amount of calories,

at the end, the time

restricted mice are lean

compared to the ad lib fed mice.

- And they could stay progressively fitter

and all they had to do

was change when they eat,

not what they eat.

- Your body needs a daily

fasting period and that

eating erratically and kind

of eating all over the day

takes away from our body's natural rhythm

to say this is when we

eat, this is when we rest,

and it's hitting a manual override button.

- We work with a circadian rhythm.

Our bodies are on a clock basically

which is aligned with the 24

hour rotation of the earth.

- The circadian rhythm

and turning on and off

of more than 10,000 genes is

the largest regulatory network

that we know that exists in human.

- Circadian rhythms in

the liver, the pancreas,

and the fat cells get

tremendously disrupted

when you eat late at night or when you eat

for more than 12 hours during the day.

- So if the liver clock

tracks when we eat,

then forget about light/dark,

what we have to be more

careful about is when we eat

and when we fast.

- And we have to stay in beat with earth

in order to be healthy.

So we really should stop

eating by 7 P.M. at the latest

because their pancreas goes to sleep.

- Just before you wake up,

somewhere around 4 A.M.,

growth hormone, adrenaline and so on,

all get pumped up.

You're basically activating

yourself for the day.

So for all those people who say oh,

you have to get up and eat

because you're not gonna have energy,

like your body has already prepared you

for everything you're gonna do.

You don't need to do it again.

- [Michael Voiceover]

And so during the day,

we need to be able to go out

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