Matthew Witten (born in Baltimore) is an American television writer for House and other shows. He also has written several mystery books, the first of which was Breakfast at Madeline's. Witten currently resides in Los Angeles with his wife and two sons. He is the son of Louis Witten and the brother of Edward Witten, both of whom are theoretical physicists.
He is credited as the writer for the Supernatural episodes "No Exit"—centering on the ghost of H. H. Holmes—and "Playthings".
Witten also teaches screenwriting for UCLA Extension Writers' Program.