Osmosis Jones

Synopsis: Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only Osmos
Production: Warner Bros. Pictures
  1 win & 7 nominations.
Rotten Tomatoes:
95 min

Dad, you have the coolest job.

I should hang out with

a better class of animals.

Oh, come on.

Have some class.

We got mixed company here.

You know, genetically speaking,

monkeys are our first cousins.

Uncle Bob's kids?

I'd agree with that.

No, I' m serious.

Some scientists say their diets

are more evolved.

This is about diets again, huh?

You should eat more fruits and

vegetables. Like monkeys do.

Honey, the reason that monkeys

eat so many fruits and vegetables...

...is because they' re not

smart enough to butcher a cow.

Your mother, bless her soul,

didn't believe the old ideas...

...about nursing and breast-feeding.

You were fed cheeseburgers as a baby.

And you' re as strong as a bull.

Smell like a cow.

High cholesterol,

but there's medicine.

An angioplasty clears it out.

You' re great, honey.

I'll start working out tomorrow.

-I'll take better care of myself.

-So you'll go on the hike with me?

First things first. Eat your lunch.

We'll talk later.

Give me that egg, pal!

Give me the egg!

Dad, stop it! What are you doing?

It's my egg! Come on!

It's just an egg!

Okay, now I gotta choke you!

Now who's evolved?

All that salad slow you down, buddy?

That's filthy.

Ten-second rule:

Hits the ground, you can

eat it within 10 seconds.

-Saliva one, what have you got?

-An egg 2-20. E-Gamma-Gamma. Over.

-Any mayo?


Slow bowel traffic....

Enzyme breakdown in ten.

When I was a rookie cell,

you could eat off this place.

Look at it now. Jeez...

...what a disgrace.

See anything, kid?

I do.

Nice genes. Got chromosomes

in all the right places.


-A toothbrush can handle this.

I wish you'd take this job

more seriously.

You see this badge?

You see this gun?

See this gooey sackus membranous

around my personhood?

-Here we go again.

-You dealing with a white blood cell!

I should fight disease in the veins!

Not here, on tartar control!

Lucky you ain't in a scab.

We got germs on that egg.

Baby! It's Ozzy time!

Probably gingivitis,

don't get carried away.

You have entered the city of Frank.

Hands up.

Surrender for digestion.

Saliva one, requesting

ground support. Over.

Bicuspid four,

we' re in the vicinity.

This is a private organism.

Don 't run.

Up spit creek without a paddle.

Don 't get me mad.

I will turn into a germicidal maniac.

Halt. Saliva Patrol.

Son of a botulism!

They swiped the patrol car!

Get out of here.

You done done it now.

Holy Frank!

He 's about to yawn!

We 're getting sucked in!

I told city hall we need more sleep!

Hold tight, kid!

Osmosis Jones to dispatch.

We got multiple germs

coming down the windpipe.

If they hit the blood stream,

we 'll be illing.





-Permission to pursue?


-You got plans for the weekend?

-Oh, yeah.

Me and my girlfriend are going

to the IKidneys to see the Stones.

Good, they could pass any day.

All units south of the stomach,

lookout for illegal organism.

Jones, you want to keep yourjob?

Wait for backup!

I can get them.

I said stay put.


-You heard the chief.

Out of ourjurisdiction.

It's lmmunity's problem.

We should get to the mouth.

-Hey, Jones!

-Chief, you'll thank me later.

Don 't think about it.

You 're in enough trouble.


Slow down! Slow down!

Wait, wait, what the--?

Shouldn't you be up in the mouth?

This is my bust. I saw him first.

You want Osmosis? You got Osmosis.

Bye-bye, cop!

Sorry, baby. But it's time

you take your medicine.

Dang. Always pulls to the right.

Dad, what's wrong? Oh, my God.

Rate this script:4.0 / 4 votes

Marc Hyman

Marc Hyman is an American screenwriter. His writing credits also include Universal Pictures Meet the Fockers , Paramount's The Perfect Score and Show Dogs. He has served as a script doctor for more than 40 produced movies. He was credited for his work on fantasy epic The Great Wall. more…

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Submitted on August 05, 2018

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