Otto F. Hoffman (May 2, 1879 – June 23, 1944) was an American film actor. He appeared in 199 films between 1915 and 1944. He was born in New York City and died in Los Angeles, California from lung cancer. Hoffman's Broadway credits include The Strange Woman (1913), The Spring Maid (1910), and A Broken Idol (1909). He was also active in stock theater productions. Hoffman debuted in film in 1906 in a production of the Edison Company in New York. Later he worked for Goldwyn Pictures.